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Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity

The axon initial segment (AIS) is a specialized structure in neurons that resides in between axonal and somatodendritic domains. The localization of the AIS in neurons is ideal for its two major functions: it serves as the site of action potential firing and helps to maintain neuron polarity. It has...

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Detalles Bibliográficos
Autores principales: Jones, Steven L., Svitkina, Tatyana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967436/
https://www.ncbi.nlm.nih.gov/pubmed/27493806
http://dx.doi.org/10.1155/2016/6808293