Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development

MLL-AF4+ infant B cell acute lymphoblastic leukemia is characterized by an early onset and dismal survival. It initiates before birth, and very little is known about the early stages of the disease’s development. Using a conditional Mll-AF4-expressing mouse model in which fusion expression is target...

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Detalles Bibliográficos
Autores principales: Barrett, Neil A., Malouf, Camille, Kapeni, Chrysa, Bacon, Wendi A., Giotopoulos, George, Jacobsen, Sten Eirik W., Huntly, Brian J., Ottersbach, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967476/
https://www.ncbi.nlm.nih.gov/pubmed/27396339
http://dx.doi.org/10.1016/j.celrep.2016.06.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967476/
https://www.ncbi.nlm.nih.gov/pubmed/27396339
http://dx.doi.org/10.1016/j.celrep.2016.06.046

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