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A multicenter phase I/II study of enzalutamide in Japanese patients with castration-resistant prostate cancer

BACKGROUND: The safety, tolerability, pharmacokinetics (PK) and anti-tumor activity of enzalutamide were investigated in patients with castration-resistant prostate cancer (CRPC) in Japan through a multicenter phase I/II study. METHODS: In phase I, patients with progressive metastatic CRPC received...

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Detalles Bibliográficos
Autores principales: Akaza, Hideyuki, Uemura, Hirotsugu, Tsukamoto, Taiji, Ozono, Seiichiro, Ogawa, Osamu, Sakai, Hideki, Oya, Mototsugu, Namiki, Mikio, Fukasawa, Satoshi, Yamaguchi, Akito, Uemura, Hiroji, Ohashi, Yasuo, Maeda, Hideki, Saito, Atsushi, Takeda, Kentaro, Naito, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967591/
https://www.ncbi.nlm.nih.gov/pubmed/26793974
http://dx.doi.org/10.1007/s10147-016-0952-6