SOX7-enforced expression promotes the expansion of adult blood progenitors and blocks B-cell development

During embryogenesis, the three SOXF transcription factors, SOX7, SOX17 and SOX18, regulate the specification of the cardiovascular system and are also involved in the development of haematopoiesis. The ectopic expression of SOX17 in both embryonic and adult blood cells enhances self-renewal. Likewi...

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Detalles Bibliográficos
Autores principales: Cuvertino, Sara, Lacaud, Georges, Kouskoff, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967825/
https://www.ncbi.nlm.nih.gov/pubmed/27411892
http://dx.doi.org/10.1098/rsob.160070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967825/
https://www.ncbi.nlm.nih.gov/pubmed/27411892
http://dx.doi.org/10.1098/rsob.160070

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