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SOX7-enforced expression promotes the expansion of adult blood progenitors and blocks B-cell development
During embryogenesis, the three SOXF transcription factors, SOX7, SOX17 and SOX18, regulate the specification of the cardiovascular system and are also involved in the development of haematopoiesis. The ectopic expression of SOX17 in both embryonic and adult blood cells enhances self-renewal. Likewi...
Autores principales: | Cuvertino, Sara, Lacaud, Georges, Kouskoff, Valerie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967825/ https://www.ncbi.nlm.nih.gov/pubmed/27411892 http://dx.doi.org/10.1098/rsob.160070 |
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