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Treatment with an orally bioavailable prodrug of 17β-estradiol alleviates hot flushes without hormonal effects in the periphery

Estrogen deprivation has a profound effect on the female brain. One of the most obvious examples of this condition is hot flushes. Although estrogens relieve these typical climacteric symptoms, many women do not want to take them owing to unwanted side-effects impacting, for example, the uterus, bre...

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Detalles Bibliográficos
Autores principales: Merchenthaler, Istvan, Lane, Malcolm, Sabnis, Gauri, Brodie, Angela, Nguyen, Vien, Prokai, Laszlo, Prokai-Tatrai, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967894/
https://www.ncbi.nlm.nih.gov/pubmed/27477453
http://dx.doi.org/10.1038/srep30721