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Treatment with an orally bioavailable prodrug of 17β-estradiol alleviates hot flushes without hormonal effects in the periphery
Estrogen deprivation has a profound effect on the female brain. One of the most obvious examples of this condition is hot flushes. Although estrogens relieve these typical climacteric symptoms, many women do not want to take them owing to unwanted side-effects impacting, for example, the uterus, bre...
Autores principales: | Merchenthaler, Istvan, Lane, Malcolm, Sabnis, Gauri, Brodie, Angela, Nguyen, Vien, Prokai, Laszlo, Prokai-Tatrai, Katalin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967894/ https://www.ncbi.nlm.nih.gov/pubmed/27477453 http://dx.doi.org/10.1038/srep30721 |
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