Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening

Sphingosine-1-phosphate (S1P) is a lysophospholipid mediator carried by the HDL-associated apoM protein in blood, regulating many physiological processes by activating the G protein-coupled S1P receptor in mammals. Despite the solved crystal structure of the apoM-S1P complex, the mechanism of S1P re...

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Detalles Bibliográficos
Autores principales: Zhang, Hansi, Pluhackova, Kristyna, Jiang, Zhenyan, Böckmann, Rainer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967915/
https://www.ncbi.nlm.nih.gov/pubmed/27476912
http://dx.doi.org/10.1038/srep30655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967915/
https://www.ncbi.nlm.nih.gov/pubmed/27476912
http://dx.doi.org/10.1038/srep30655

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