HCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2

Hepatitis C virus (HCV) infection is a leading cause of liver fibrosis, especially in developing countries. The process is characterized by the excess accumulation of ECM that may lead, over time, to hepatic cirrhosis, liver failure and also to hepatocarcinoma. The direct role of HCV in promoting fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Granato, M., Zompetta, C., Vescarelli, E., Rizzello, C., Cardi, A., Valia, S., Antonelli, G., Marchese, C., Torrisi, M. R., Faggioni, A., Cirone, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967919/
https://www.ncbi.nlm.nih.gov/pubmed/27476557
http://dx.doi.org/10.1038/srep30649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967919/
https://www.ncbi.nlm.nih.gov/pubmed/27476557
http://dx.doi.org/10.1038/srep30649

Ejemplares similares