Oligonucleotide‐induced alternative splicing of serotonin 2C receptor reduces food intake

The serotonin 2C receptor regulates food uptake, and its activity is regulated by alternative pre‐mRNA splicing. Alternative exon skipping is predicted to generate a truncated receptor protein isoform, whose existence was confirmed with a new antiserum. The truncated receptor sequesters the full‐len...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaiyi, Shen, Manli, Gresch, Paul J, Ghamari‐Langroudi, Masoud, Rabchevsky, Alexander G, Emeson, Ronald B, Stamm, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967942/
https://www.ncbi.nlm.nih.gov/pubmed/27406820
http://dx.doi.org/10.15252/emmm.201506030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967942/
https://www.ncbi.nlm.nih.gov/pubmed/27406820
http://dx.doi.org/10.15252/emmm.201506030

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