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The use of HIV-1 integration site analysis information in clinical studies aiming at HIV cure

The mechanisms for the establishment and the persistence of the latent HIV-1 reservoir remain to be completely defined. HIV-1 infection is characterised by the integration of the reverse transcribed proviral DNA into the host's genome. This integrated proviral DNA can remain replication silent,...

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Detalles Bibliográficos
Autores principales: Kiselinova, Maja, De Spiegelaere, Ward, Vandekerckhove, Linos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mediscript Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967970/
https://www.ncbi.nlm.nih.gov/pubmed/27482458