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The use of CrossMAb technology for the generation of bi- and multispecific antibodies
The major challenge in the generation of bispecific IgG antibodies is enforcement of the correct heavy and light chain association. The correct association of generic light chains can be enabled using immunoglobulin domain crossover, known as CrossMAb technology, which can be combined with approache...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968094/ https://www.ncbi.nlm.nih.gov/pubmed/27285945 http://dx.doi.org/10.1080/19420862.2016.1197457 |