Assessing in vivo dynamics of multiple quality attributes from a therapeutic IgG4 monoclonal antibody circulating in cynomolgus monkey

Characterization of biopharmaceutical proteins and assessment and understanding of the critical quality attributes (CQAs) is a significant part of biopharmaceutical product development and is routinely performed in vitro. In contrast, systematic analysis of the quality attributes in vivo is not as w...

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Detalles Bibliográficos
Autores principales: Li, Yinyin, Huang, Yu, Ferrant, Janine, Lyubarskaya, Yelena, Zhang, Yue (Emma), Li, Siyang (Peter), Wu, Shiaw-Lin (Billy)
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968097/
https://www.ncbi.nlm.nih.gov/pubmed/27030286
http://dx.doi.org/10.1080/19420862.2016.1167298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968097/
https://www.ncbi.nlm.nih.gov/pubmed/27030286
http://dx.doi.org/10.1080/19420862.2016.1167298

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