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Essential control of mitochondrial morphology and function by chaperone-mediated autophagy through degradation of PARK7
As a selective degradation system, chaperone-mediated autophagy (CMA) is essential for maintaining cellular homeostasis and survival under stress conditions. Increasing evidence points to an important role for the dysfunction of CMA in the pathogenesis of Parkinson disease (PD). However, the mechani...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968227/ https://www.ncbi.nlm.nih.gov/pubmed/27171370 http://dx.doi.org/10.1080/15548627.2016.1179401 |