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Iron-depletion promotes mitophagy to maintain mitochondrial integrity in pathogenic yeast Candida glabrata

Candida glabrata, a haploid budding yeast, is the cause of severe systemic infections in immune-compromised hosts. The amount of free iron supplied to C. glabrata cells during systemic infections is severely limited by iron-chelating proteins such as transferrin. Thus, the iron-deficiency response i...

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Detalles Bibliográficos
Autores principales: Nagi, Minoru, Tanabe, Koichi, Nakayama, Hironobu, Ueno, Keigo, Yamagoe, Satoshi, Umeyama, Takashi, Ohno, Hideaki, Miyazaki, Yoshitsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968229/
https://www.ncbi.nlm.nih.gov/pubmed/27347716
http://dx.doi.org/10.1080/15548627.2016.1183080