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Pharmacological Inhibition of Myostatin Protects Against Atrophy and Weakness after ACL Tear

OBJECTIVES: Many patients who suffer ACL tears have persistent atrophy and weakness even after rehabilitation. Myostatin is a cytokine that directly induces muscle atrophy, and previous studies using rodent models and patients have demonstrated an up regulation of myostatin after ACL tear. Using a p...

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Detalles Bibliográficos
Autores principales: Wolfe, Caroline Nicole, Gumucio, Jonathan P., Grekin, Jeremy, Khouri, Roger Karl, Bedi, Asheesh, Mendias, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968297/
http://dx.doi.org/10.1177/2325967116S00138