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Ancient pathogen-driven adaptation triggers increased susceptibility to non-celiac wheat sensitivity in present-day European populations

BACKGROUND: Non-celiac wheat sensitivity is an emerging wheat-related syndrome showing peak prevalence in Western populations. Recent studies hypothesize that new gliadin alleles introduced in the human diet by replacement of ancient wheat with modern varieties can prompt immune responses mediated b...

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Detalles Bibliográficos
Autores principales: Sazzini, Marco, De Fanti, Sara, Cherubini, Anna, Quagliariello, Andrea, Profiti, Giuseppe, Martelli, Pier Luigi, Casadio, Rita, Ricci, Chiara, Campieri, Massimo, Lanzini, Alberto, Volta, Umberto, Caio, Giacomo, Franceschi, Claudio, Spisni, Enzo, Luiselli, Donata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968434/
https://www.ncbi.nlm.nih.gov/pubmed/27551316
http://dx.doi.org/10.1186/s12263-016-0532-4