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Novel p53 target gene FUCA1 encodes a fucosidase and regulates growth and survival of cancer cells

The tumor suppressor p53 functions by inducing the transcription of a collection of target genes. We previously attempted to identify p53 target genes by microarray expression and ChIP‐sequencing analyses. In this study, we describe a novel p53 target gene, FUCA1, which encodes a fucosidase. Althoug...

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Detalles Bibliográficos
Autores principales: Ezawa, Issei, Sawai, Yuichiro, Kawase, Tatsuya, Okabe, Atsushi, Tsutsumi, Shuichi, Ichikawa, Hitoshi, Kobayashi, Yuka, Tashiro, Fumio, Namiki, Hideo, Kondo, Tadashi, Semba, Kentaro, Aburatani, Hiroyuki, Taya, Yoichi, Nakagama, Hitoshi, Ohki, Rieko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968591/
https://www.ncbi.nlm.nih.gov/pubmed/26998741
http://dx.doi.org/10.1111/cas.12933