Validation of chemical compound library screening for transcriptional co‐activator with PDZ‐binding motif inhibitors using GFP‐fused transcriptional co‐activator with PDZ‐binding motif

Transcriptional co‐activator with PDZ‐binding motif (TAZ) plays versatile roles in cell proliferation and differentiation. It is phosphorylated by large tumor suppressor kinases, the core kinases of the tumor‐suppressive Hippo pathway. Phosphorylation induces the cytoplasmic accumulation of TAZ and...

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Detalles Bibliográficos
Autores principales: Nagashima, Shunta, Maruyama, Junichi, Kawano, Shodai, Iwasa, Hiroaki, Nakagawa, Kentaro, Ishigami‐Yuasa, Mari, Kagechika, Hiroyuki, Nishina, Hiroshi, Hata, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968592/
https://www.ncbi.nlm.nih.gov/pubmed/27009852
http://dx.doi.org/10.1111/cas.12936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968592/
https://www.ncbi.nlm.nih.gov/pubmed/27009852
http://dx.doi.org/10.1111/cas.12936

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