Retinal Structure and Gene Therapy Outcome in Retinoschisin-Deficient Mice Assessed by Spectral-Domain Optical Coherence Tomography

PURPOSE: Spectral-domain optical coherence tomography (SD-OCT) was used to characterize the retinal phenotype, natural history, and treatment responses in a mouse model of X-linked retinoschisis (Rs1-KO) and to identify new structural markers of AAV8-mediated gene therapy outcome. METHODS: Optical c...

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Detalles Bibliográficos
Autores principales: Zeng, Yong, Petralia, Ronald S., Vijayasarathy, Camasamudram, Wu, Zhijian, Hiriyanna, Suja, Song, Hongman, Wang, Ya-Xian, Sieving, Paul A., Bush, Ronald A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968785/
https://www.ncbi.nlm.nih.gov/pubmed/27409484
http://dx.doi.org/10.1167/iovs.15-18920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968785/
https://www.ncbi.nlm.nih.gov/pubmed/27409484
http://dx.doi.org/10.1167/iovs.15-18920

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