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Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis

Podocytes are terminally differentiated glomerular epithelial cells. Podocyte loss has been found in many renal diseases. Cdk5 is a cyclin-dependent protein kinase which is predominantly regulated by p35. To study the role of Cdk5/p35 in podocyte survival, we first applied western blotting (WB) anal...

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Detalles Bibliográficos
Autores principales: Zheng, Ya-Li, Zhang, Xia, Fu, Hai-Xia, Guo, Mei, Shukla, Varsha, Amin, Niranjana D., E, Jing, Bao, Li, Luo, Hong-Yan, Li, Bo, Lu, Xiao-Hua, Gao, Yong-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968817/
https://www.ncbi.nlm.nih.gov/pubmed/27479491
http://dx.doi.org/10.1371/journal.pone.0160252