Mild Alkalization Acutely Triggers the Warburg Effect by Enhancing Hexokinase Activity via Voltage-Dependent Anion Channel Binding

To fully understand the glycolytic behavior of cancer cells, it is important to recognize how it is linked to pH dynamics. Here, we evaluated the acute effects of mild acidification and alkalization on cancer cell glucose uptake and glycolytic flux and investigated the role of hexokinase (HK). Cance...

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Detalles Bibliográficos
Autores principales: Quach, Cung Hoa Thien, Jung, Kyung-Ho, Lee, Jin Hee, Park, Jin Won, Moon, Seung Hwan, Cho, Young Seok, Choe, Yearn Seong, Lee, Kyung-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968818/
https://www.ncbi.nlm.nih.gov/pubmed/27479079
http://dx.doi.org/10.1371/journal.pone.0159529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968818/
https://www.ncbi.nlm.nih.gov/pubmed/27479079
http://dx.doi.org/10.1371/journal.pone.0159529

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