A Three-Pulse Release Tablet for Amoxicillin: Preparation, Pharmacokinetic Study and Physiologically Based Pharmacokinetic Modeling

BACKGROUND: Amoxicillin is a commonly used antibiotic which has a short half-life in human. The frequent administration of amoxicillin is often required to keep the plasma drug level in an effective range. The short dosing interval of amoxicillin could also cause some side effects and drug resistanc...

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Detalles Bibliográficos
Autores principales: Li, Jin, Chai, Hongyu, Li, Yang, Chai, Xuyu, Zhao, Yan, Zhao, Yunfan, Tao, Tao, Xiang, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968835/
https://www.ncbi.nlm.nih.gov/pubmed/27479702
http://dx.doi.org/10.1371/journal.pone.0160260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968835/
https://www.ncbi.nlm.nih.gov/pubmed/27479702
http://dx.doi.org/10.1371/journal.pone.0160260

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