An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection

Scrub typhus is a neglected tropical disease, caused by Orientia tsutsugamushi, a Gram-negative bacterium that is transmitted to mammalian hosts during feeding by Leptotrombidium mites and replicates predominantly within endothelial cells. Most studies of scrub typhus in animal models have utilized...

Descripción completa

Detalles Bibliográficos
Autores principales: Soong, Lynn, Mendell, Nicole L., Olano, Juan P., Rockx-Brouwer, Dedeke, Xu, Guang, Goez-Rivillas, Yenny, Drom, Claire, Shelite, Thomas R., Valbuena, Gustavo, Walker, David H., Bouyer, Donald H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968841/
https://www.ncbi.nlm.nih.gov/pubmed/27479584
http://dx.doi.org/10.1371/journal.pntd.0004884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968841/
https://www.ncbi.nlm.nih.gov/pubmed/27479584
http://dx.doi.org/10.1371/journal.pntd.0004884

Ejemplares similares