An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection

Scrub typhus is a neglected tropical disease, caused by Orientia tsutsugamushi, a Gram-negative bacterium that is transmitted to mammalian hosts during feeding by Leptotrombidium mites and replicates predominantly within endothelial cells. Most studies of scrub typhus in animal models have utilized...

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Detalles Bibliográficos
Autores principales: Soong, Lynn, Mendell, Nicole L., Olano, Juan P., Rockx-Brouwer, Dedeke, Xu, Guang, Goez-Rivillas, Yenny, Drom, Claire, Shelite, Thomas R., Valbuena, Gustavo, Walker, David H., Bouyer, Donald H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968841/
https://www.ncbi.nlm.nih.gov/pubmed/27479584
http://dx.doi.org/10.1371/journal.pntd.0004884

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