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Potential predictive role of chemotherapy-induced changes of soluble CD40 ligand in untreated advanced pancreatic ductal adenocarcinoma

Pancreas ductal adenocarcinoma lacks predictive biomarkers. CD40 is a member of the tumor necrosis factor superfamily. CD40–sCD40L interaction is considered to contribute to the promotion of tumor cell growth and angiogenesis. The aim of the present study was to investigate the role of serum sCD40L...

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Detalles Bibliográficos
Autores principales: Azzariti, Amalia, Brunetti, Oronzo, Porcelli, Letizia, Graziano, Giusi, Iacobazzi, Rosa Maria, Signorile, Michele, Scarpa, Aldo, Lorusso, Vito, Silvestris, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968860/
https://www.ncbi.nlm.nih.gov/pubmed/27555786
http://dx.doi.org/10.2147/OTT.S106496