Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life

Asthma is a chronic inflammatory airways disease that usually begins in early life and involves gene-environment interactions. Although most asthma exhibits allergic inflammation, many allergic individuals do not have asthma. Here, we report how the asthma gene a disintegrin and metalloprotease 33 (...

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Detalles Bibliográficos
Autores principales: Davies, Elizabeth R., Kelly, Joanne F.C., Howarth, Peter H., Wilson, David I., Holgate, Stephen T., Davies, Donna E., Whitsett, Jeffrey A., Haitchi, Hans Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968941/
https://www.ncbi.nlm.nih.gov/pubmed/27489884
http://dx.doi.org/10.1172/jci.insight.87632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968941/
https://www.ncbi.nlm.nih.gov/pubmed/27489884
http://dx.doi.org/10.1172/jci.insight.87632

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