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Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life
Asthma is a chronic inflammatory airways disease that usually begins in early life and involves gene-environment interactions. Although most asthma exhibits allergic inflammation, many allergic individuals do not have asthma. Here, we report how the asthma gene a disintegrin and metalloprotease 33 (...
Autores principales: | Davies, Elizabeth R., Kelly, Joanne F.C., Howarth, Peter H., Wilson, David I., Holgate, Stephen T., Davies, Donna E., Whitsett, Jeffrey A., Haitchi, Hans Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968941/ https://www.ncbi.nlm.nih.gov/pubmed/27489884 http://dx.doi.org/10.1172/jci.insight.87632 |
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