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Mechanistic signs of double-barreled structure in a fluoride ion channel

The Fluc family of F(−) ion channels protects prokaryotes and lower eukaryotes from the toxicity of environmental F(−). In bacteria, these channels are built as dual-topology dimers whereby the two subunits assemble in antiparallel transmembrane orientation. Recent crystal structures suggested that...

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Detalles Bibliográficos
Autores principales: Last, Nicholas B, Kolmakova-Partensky, Ludmila, Shane, Tania, Miller, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969038/
https://www.ncbi.nlm.nih.gov/pubmed/27449280
http://dx.doi.org/10.7554/eLife.18767