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Extravascular modified lipoproteins: a role in the propagation of diabetic retinopathy in a mouse model of type 1 diabetes

AIMS/HYPOTHESIS: We aimed to determine whether plasma lipoproteins, after leakage into the retina and modification by glycation and oxidation, contribute to the development of diabetic retinopathy in a mouse model of type 1 diabetes. METHODS: To simulate permeation of plasma lipoproteins into retina...

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Detalles Bibliográficos
Autores principales: Yu, Jeremy Y., Du, Mei, Elliott, Michael H., Wu, Mingyuan, Fu, Dongxu, Yang, Shihe, Basu, Arpita, Gu, Xiaowu, Ma, Jian-Xing, Aston, Christopher E., Lyons, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969344/
https://www.ncbi.nlm.nih.gov/pubmed/27306616
http://dx.doi.org/10.1007/s00125-016-4012-6