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CTLA-4 affects expression of key cell cycle regulators of G0/G1 phase in neoplastic lymphocytes from patients with chronic lymphocytic leukaemia

Previously, we showed that cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) is overexpressed in chronic lymphocytic leukaemia (CLL) and its expression is correlated with the expression of the major regulators of G1 phase progression: cyclins D2 and D3, and cyclin-dependent kinase inhibitory prot...

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Detalles Bibliográficos
Autores principales: Ciszak, Lidia, Frydecka, Irena, Wolowiec, Dariusz, Szteblich, Aleksandra, Kosmaczewska, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969362/
https://www.ncbi.nlm.nih.gov/pubmed/26003188
http://dx.doi.org/10.1007/s10238-015-0360-7