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Detection of cis- and trans-acting Factors in DNA Structure-Induced Genetic Instability Using In silico and Cellular Approaches

Sequences that can adopt alternative DNA structures (i.e., non-B DNA) are very abundant in mammalian genomes, and recent studies have revealed many important biological functions of non-B DNA structures in chromatin remodeling, DNA replication, transcription, and genetic instability. Here, we provid...

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Detalles Bibliográficos
Autores principales: Wang, Guliang, Zhao, Junhua, Vasquez, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969553/
https://www.ncbi.nlm.nih.gov/pubmed/27532010
http://dx.doi.org/10.3389/fgene.2016.00135