Cargando…

Curcumin Veto the Effects of Osteopontin (OPN) Specific Inhibitor on Leukemic Stem Cell Colony Forming Potential via Promotion of OPN Overexpression

Background: Acute myeloid leukemia (AML) is an immunophenotypically heterogeneous malignant disease, in which CD34 positivity is associated with poor prognosis. Osteopontin (OPN) plays different roles in physiologic and pathologic conditions like: survival, metastasis and cell protection from cytoto...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohammadi, Saeed, Ghaffari, Seyed H., Shaiegan, Mojgan, Nikogoftar Zarif, Mahin, Nikbakht, Mohsen, Alimoghaddam, Kamran, Ghavamzadeh, Ardeshir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969556/
https://www.ncbi.nlm.nih.gov/pubmed/27489587