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Spatial control of lipid droplet proteins by the ERAD ubiquitin ligase Doa10

The endoplasmic reticulum (ER) plays a central role in the biogenesis of most membrane proteins. Among these are proteins localized to the surface of lipid droplets (LDs), fat storage organelles delimited by a phospholipid monolayer. The LD monolayer is often continuous with the membrane of the ER a...

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Detalles Bibliográficos
Autores principales: Ruggiano, Annamaria, Mora, Gabriel, Buxó, Laura, Carvalho, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969576/
https://www.ncbi.nlm.nih.gov/pubmed/27357570
http://dx.doi.org/10.15252/embj.201593106