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Regulation of StAR by the N-terminal Domain and Coinduction of SIK1 and TIS11b/Znf36l1 in Single Cells

The cholesterol transfer function of steroidogenic acute regulatory protein (StAR) is uniquely integrated into adrenal cells, with mRNA translation and protein kinase A (PKA) phosphorylation occurring at the mitochondrial outer membrane (OMM). The StAR C-terminal cholesterol-binding domain (CBD) ini...

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Detalles Bibliográficos
Autores principales: Lee, Jinwoo, Tong, Tiegang, Duan, Haichuan, Foong, Yee Hoon, Musaitif, Ibrahim, Yamazaki, Takeshi, Jefcoate, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969582/
https://www.ncbi.nlm.nih.gov/pubmed/27531991
http://dx.doi.org/10.3389/fendo.2016.00107