Identification of disease-specific motifs in the antibody specificity repertoire via next-generation sequencing

Disease-specific antibodies can serve as highly effective biomarkers but have been identified for only a relatively small number of autoimmune diseases. A method was developed to identify disease-specific binding motifs through integration of bacterial display peptide library screening, next-generat...

Descripción completa

Detalles Bibliográficos
Autores principales: Pantazes, Robert J., Reifert, Jack, Bozekowski, Joel, Ibsen, Kelly N., Murray, Joseph A., Daugherty, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969583/
https://www.ncbi.nlm.nih.gov/pubmed/27481573
http://dx.doi.org/10.1038/srep30312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969583/
https://www.ncbi.nlm.nih.gov/pubmed/27481573
http://dx.doi.org/10.1038/srep30312

Ejemplares similares