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Identification of disease-specific motifs in the antibody specificity repertoire via next-generation sequencing
Disease-specific antibodies can serve as highly effective biomarkers but have been identified for only a relatively small number of autoimmune diseases. A method was developed to identify disease-specific binding motifs through integration of bacterial display peptide library screening, next-generat...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969583/ https://www.ncbi.nlm.nih.gov/pubmed/27481573 http://dx.doi.org/10.1038/srep30312 |