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Disruption of dmc1 Produces Abnormal Sperm in Medaka (Oryzias latipes)

DMC1 is a recombinase that is essential for meiotic synapsis. Experiments in extensive species of eukaryotes have indicated the independent role of DMC1 in repairing double strand breaks (DSBs) produced during meiosis I. Mutation of dmc1 in mice and human often leads to obstacles in spermatogenesis...

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Detalles Bibliográficos
Autores principales: Chen, Ji, Cui, Xiaojuan, Jia, Shaoting, Luo, Daji, Cao, Mengxi, Zhang, Yunsheng, Hu, Hongling, Huang, Kaiyao, Zhu, Zuoyan, Hu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969596/
https://www.ncbi.nlm.nih.gov/pubmed/27480068
http://dx.doi.org/10.1038/srep30912