Quality control of nonstop membrane proteins at the ER membrane and in the cytosol

Since messenger RNAs without a stop codon (nonstop mRNAs) for organelle-targeted proteins and their translation products (nonstop proteins) generate clogged translocon channels as well as stalled ribosomes, cells have mechanisms to degrade nonstop mRNAs and nonstop proteins and to clear the transloc...

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Detalles Bibliográficos
Autores principales: Arakawa, Shunsuke, Yunoki, Kaori, Izawa, Toshiaki, Tamura, Yasushi, Nishikawa, Shuh-ichi, Endo, Toshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969602/
https://www.ncbi.nlm.nih.gov/pubmed/27481473
http://dx.doi.org/10.1038/srep30795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969602/
https://www.ncbi.nlm.nih.gov/pubmed/27481473
http://dx.doi.org/10.1038/srep30795

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