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Interferon gamma-induced apoptosis of head and neck squamous cell carcinoma is connected to indoleamine-2,3-dioxygenase via mitochondrial and ER stress-associated pathways

BACKGROUND: Tumor response to immunotherapy is the consequence of a concerted crosstalk between cytokines and effector cells. Interferon gamma (IFNγ) is one of the common cytokines coordinating tumor immune response and the associated biological consequences. Although the role of IFNγ in the modulat...

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Detalles Bibliográficos
Autores principales: El Jamal, Siraj M., Taylor, Erin B., Abd Elmageed, Zakaria Y., Alamodi, Abdulhadi A., Selimovic, Denis, Alkhateeb, Abdulaziz, Hannig, Matthias, Hassan, Sofie Y., Santourlidis, Simeon, Friedlander, Paul L., Haikel, Youssef, Vijaykumar, Srinivasan, Kandil, Emad, Hassan, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969639/
https://www.ncbi.nlm.nih.gov/pubmed/27486476
http://dx.doi.org/10.1186/s13008-016-0023-4