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Interferon gamma-induced apoptosis of head and neck squamous cell carcinoma is connected to indoleamine-2,3-dioxygenase via mitochondrial and ER stress-associated pathways
BACKGROUND: Tumor response to immunotherapy is the consequence of a concerted crosstalk between cytokines and effector cells. Interferon gamma (IFNγ) is one of the common cytokines coordinating tumor immune response and the associated biological consequences. Although the role of IFNγ in the modulat...
Autores principales: | El Jamal, Siraj M., Taylor, Erin B., Abd Elmageed, Zakaria Y., Alamodi, Abdulhadi A., Selimovic, Denis, Alkhateeb, Abdulaziz, Hannig, Matthias, Hassan, Sofie Y., Santourlidis, Simeon, Friedlander, Paul L., Haikel, Youssef, Vijaykumar, Srinivasan, Kandil, Emad, Hassan, Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969639/ https://www.ncbi.nlm.nih.gov/pubmed/27486476 http://dx.doi.org/10.1186/s13008-016-0023-4 |
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