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Overexpression of the miR-141/200c cluster promotes the migratory and invasive ability of triple-negative breast cancer cells through the activation of the FAK and PI3K/AKT signaling pathways by secreting VEGF-A

BACKGROUND: The role of microRNA-200 (miR-200) family members in the migration and invasion of breast cancer is controversial. This study investigated the mechanisms by which the miR-200 family members modulated the migratory and invasive abilities of an aggressive triple-negative breast cancer (TNB...

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Detalles Bibliográficos
Autores principales: Choi, Sul Ki, Kim, Hoe Suk, Jin, Tiefeng, Hwang, Eun Hye, Jung, Minji, Moon, Woo Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969651/
https://www.ncbi.nlm.nih.gov/pubmed/27484639
http://dx.doi.org/10.1186/s12885-016-2620-7