Gtpbp2 is a positive regulator of Wnt signaling and maintains low levels of the Wnt negative regulator Axin

BACKGROUND: Canonical Wnt signals, transduced by stabilized β-catenin, play similar roles across animals in maintaining stem cell pluripotency, regulating cell differentiation, and instructing normal embryonic development. Dysregulated Wnt/β-catenin signaling causes diseases and birth defects, and a...

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Detalles Bibliográficos
Autores principales: Gillis, William Q., Kirmizitas, Arif, Iwasaki, Yasuno, Ki, Dong-Hyuk, Wyrick, Jonathan M., Thomsen, Gerald H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969687/
https://www.ncbi.nlm.nih.gov/pubmed/27484226
http://dx.doi.org/10.1186/s12964-016-0138-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969687/
https://www.ncbi.nlm.nih.gov/pubmed/27484226
http://dx.doi.org/10.1186/s12964-016-0138-x

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