Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer’s Disease

Heat shock proteins (Hsps) have chaperone activity and play a pivotal role in the homeostasis of proteins by preventing misfolding, by clearing aggregated and damaged proteins from cells, and by maintaining proteins in an active state. Alzheimer’s disease (AD) is thought to be caused by amyloid-β pe...

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Detalles Bibliográficos
Autores principales: Kasza, Ágnes, Hunya, Ákos, Frank, Zsuzsa, Fülöp, Ferenc, Török, Zsolt, Balogh, Gábor, Sántha, Miklós, Bálind, Árpád, Bernáth, Sándor, Blundell, Katie L.I.M., Prodromou, Chrisostomos, Horváth, Ibolya, Zeiler, Hans-Joachim, Hooper, Philip L., Vigh, László, Penke, Botond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969717/
https://www.ncbi.nlm.nih.gov/pubmed/27163800
http://dx.doi.org/10.3233/JAD-150860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969717/
https://www.ncbi.nlm.nih.gov/pubmed/27163800
http://dx.doi.org/10.3233/JAD-150860

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