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Activation of Wnt signaling promotes hippocampal neurogenesis in experimental autoimmune encephalomyelitis

BACKGROUND: Disease progression in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), as one of its animal models, is characterized by demyelination and neuronal damage in white and gray matter structures, including the hippocampus. It is thought that dysfunction of the hip...

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Detalles Bibliográficos
Autores principales: Schneider, Reiner, Koop, Barbara, Schröter, Friederike, Cline, Jason, Ingwersen, Jens, Berndt, Carsten, Hartung, Hans-Peter, Aktas, Orhan, Prozorovski, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969720/
https://www.ncbi.nlm.nih.gov/pubmed/27480121
http://dx.doi.org/10.1186/s13024-016-0117-0