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Activation of Wnt signaling promotes hippocampal neurogenesis in experimental autoimmune encephalomyelitis
BACKGROUND: Disease progression in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), as one of its animal models, is characterized by demyelination and neuronal damage in white and gray matter structures, including the hippocampus. It is thought that dysfunction of the hip...
Autores principales: | Schneider, Reiner, Koop, Barbara, Schröter, Friederike, Cline, Jason, Ingwersen, Jens, Berndt, Carsten, Hartung, Hans-Peter, Aktas, Orhan, Prozorovski, Tim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969720/ https://www.ncbi.nlm.nih.gov/pubmed/27480121 http://dx.doi.org/10.1186/s13024-016-0117-0 |
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