Kidney epithelium specific deletion of kelch-like ECH-associated protein 1 (Keap1) causes hydronephrosis in mice

BACKGROUND: Transcription factor Nrf2 protects from experimental acute kidney injury (AKI) and is promising to limit progression in human chronic kidney disease (CKD) by upregulating multiple antioxidant genes. We recently demonstrated that deletion of Keap1, the endogenous inhibitor of Nrf2, in T l...

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Detalles Bibliográficos
Autores principales: Noel, Sanjeev, Arend, Lois J., Bandapalle, Samatha, Reddy, Sekhar P., Rabb, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969727/
https://www.ncbi.nlm.nih.gov/pubmed/27484495
http://dx.doi.org/10.1186/s12882-016-0310-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969727/
https://www.ncbi.nlm.nih.gov/pubmed/27484495
http://dx.doi.org/10.1186/s12882-016-0310-y

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