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Immunogenicity and functional characterization of Leishmania-derived hepatitis C virus envelope glycoprotein complex

Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 are the main inducers of a cross-neutralizing antibody response which plays an important role in the early phase of viral infection. Correctly folded and immunologically active E1E2 complex can be expressed in mammalian cells, though the produ...

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Detalles Bibliográficos
Autores principales: Grzyb, Katarzyna, Czarnota, Anna, Brzozowska, Agnieszka, Cieślik, Anna, Rąbalski, Łukasz, Tyborowska, Jolanta, Bieńkowska-Szewczyk, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969751/
https://www.ncbi.nlm.nih.gov/pubmed/27481352
http://dx.doi.org/10.1038/srep30627