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Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles

The process of ion channel gating—opening and closing—involves local and global structural changes in the channel in response to external stimuli. Conformational changes depend on the energetic landscape that underlies the transition between closed and open states, which plays a key role in ion chan...

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Detalles Bibliográficos
Autores principales: Kim, Dorothy M., Dikiy, Igor, Upadhyay, Vikrant, Posson, David J., Eliezer, David, Nimigean, Crina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969796/
https://www.ncbi.nlm.nih.gov/pubmed/27432996
http://dx.doi.org/10.1085/jgp.201611602