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Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca(2+) channel subfamily: Ca(V)4
Bilaterian voltage-gated Na(+) channels (Na(V)) evolved from voltage-gated Ca(2+) channels (Ca(V)). The Drosophila melanogaster Na(+) channel 1 (DSC1), which features a D-E-E-A selectivity filter sequence that is intermediate between Ca(V) and Na(V) channels, is evidence of this evolution. Phylogene...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969797/ https://www.ncbi.nlm.nih.gov/pubmed/27432995 http://dx.doi.org/10.1085/jgp.201611614 |