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Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca(2+) channel subfamily: Ca(V)4

Bilaterian voltage-gated Na(+) channels (Na(V)) evolved from voltage-gated Ca(2+) channels (Ca(V)). The Drosophila melanogaster Na(+) channel 1 (DSC1), which features a D-E-E-A selectivity filter sequence that is intermediate between Ca(V) and Na(V) channels, is evidence of this evolution. Phylogene...

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Detalles Bibliográficos
Autores principales: Gosselin-Badaroudine, Pascal, Moreau, Adrien, Simard, Louis, Cens, Thierry, Rousset, Matthieu, Collet, Claude, Charnet, Pierre, Chahine, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969797/
https://www.ncbi.nlm.nih.gov/pubmed/27432995
http://dx.doi.org/10.1085/jgp.201611614